Immunopsychiatry & Mast Cell Activation Syndrome (MCAS)

Psychiatric symptoms do not exist in isolation from the rest of the body. For some individuals, conditions such as Mast Cell Activation Syndrome (MCAS) and other neuroimmune disorders may contribute to symptoms including anxiety, panic attacks, insomnia, depression, brain fog, sensory sensitivity, medication intolerance, and emotional dysregulation. These symptoms are real, physiological, and deserve thoughtful medical evaluation rather than dismissal.

Optimal psychiatric care recognizes the complex relationship between the brain, nervous system, immune system, hormones, sleep, and overall physical health. At Holistic Sleep Care, we use an evidence-informed, comprehensive approach to evaluate whether mast cell activation or other medical conditions may be contributing to psychiatric symptoms while recognizing that these conditions remain an evolving area of medical research. Our evaluations are guided by the current Consensus-2 diagnostic framework and are performed in collaboration with your existing medical team whenever appropriate.

Through a comprehensive psychiatric assessment, medication management, sleep evaluation, and close collaboration with your allergist, primary care provider, and other specialists, we work to identify both the psychological and physiological factors that may be affecting your mental health. Our goal is not to replace your medical specialists but to ensure that psychiatric symptoms receive the same careful medical consideration as any other health concern.

Whether you have an established diagnosis of MCAS, suspect that a neuroimmune condition may be contributing to your symptoms, or have spent years searching for answers to unexplained insomnia, anxiety, medication sensitivity, or cognitive changes, we are here to listen, investigate thoughtfully, and advocate for comprehensive, evidence-based care.

Together, we will work toward improving your sleep, stabilizing your nervous system, reducing unnecessary suffering, and helping you regain confidence in both your health and your future.

What Makes ImmunoPsychiatry Unique?

The Brain-Body Connection

The brain does not function independently of the rest of the body. The immune system, autonomic nervous system, endocrine system, gastrointestinal tract, sleep, nutrition, and chronic inflammation all influence brain function. Neuroimmune psychiatry recognizes these complex interactions and considers how underlying medical conditions may contribute to psychiatric symptoms.

Autonomic Nervous System Disorders

Disorders of autonomic regulation, such as Postural Orthostatic Tachycardia Syndrome (POTS), Neurocardiogenic Syncope, and Orthostatic Hypotension, can present with symptoms that closely resemble anxiety disorders, panic attacks, ADHD, or chronic fatigue. Evaluation of dizziness, tachycardia, exercise intolerance, and orthostatic symptoms may help identify when further medical assessment is appropriate.

Mast Cell Activation & Immune Dysregulation

Mast Cell Activation Syndrome (MCAS) and related mast cell disorders may contribute to symptoms such as insomnia, anxiety, panic, brain fog, medication sensitivity, sensory overload, flushing, gastrointestinal symptoms, and autonomic dysfunction. Because these symptoms often overlap with psychiatric disorders, thoughtful assessment and collaboration with allergy and immunology specialists are essential.

Comprehensive Assessment

Comprehensive psychiatric evaluations that explore the biological, psychological, and social factors influencing your mental health. Assessments include a detailed review of symptoms, sleep, medical history, medications, nervous system function, and lifestyle to develop an individualized treatment plan tailored to your needs.

Medical Differential Evaluation

We evaluate for potential medical contributors—including immune dysfunction, autonomic disorders, hormonal changes, sleep disorders, nutritional deficiencies, medication effects, and other conditions that may warrant further investigation. This evidence-informed approach helps ensure that important medical conditions are not overlooked.

Collaborative Care Coordination

We work collaboratively with your primary care provider and other specialists—including allergists, neurologists, cardiologists, rheumatologists, gastroenterologists, and sleep medicine providers—to promote coordinated, comprehensive care. Open communication between providers helps ensure that treatment decisions support your overall health and well-being.

Patient Advocacy

Patients with complex or unexplained symptoms often face years of uncertainty before finding answers. We are committed to listening carefully, validating your concerns, and advocating for thoughtful, evidence-based medical evaluation when appropriate. Through comprehensive documentation, coordination of care, and collaboration with your healthcare team, we help ensure your symptoms are taken seriously and your voice is heard.